Name: Danny Ben-Zvi

Title： Investigator

Email: Danny.ben-zvi@mail.huji.ac.il

Tel: +972542772406

Research Interests

We take a systems biology approach to Investigate the weight-loss dependent and independent outcomes of bariatric (weight-loss) surgeries using mathematical models, computational tools, rodent models and human data.  

Ten Selected Papers

*co-corresponding authors; #co-first authors

1. Sleeve Gastrectomy Is Associated With A Greater Reduction in Plasma Liver Enzymes than Bypass Surgeries - A Registry-Based 2-Year Follow-Up Analysis. Azulai S, Grinbaum R, Begblaibter N, Eldar SM, Rubin M, Ben-Haroush Schyr R, Romano-Zelekha O, and Ben-Zvi D. Accepted to Journal of Clinical Medicine (2021)

2. Time-dependent molecular responses differ between gastric bypass and dieting but are conserved across species. Ben-Zvi D*, Meoli D, Abidi W, Nestoridi E, Panciotti C, Castillo E, Pizarro P, Shirley E, Gourash W, Thompson C, Munoz R, Anafi R, Coucoulas A, Stylopoulos N*. Cell Metabolism. Aug 7;28(2):310-323 (2018)

3. Sleeve gastrectomy improves glycemia independent of weight loss by restoring hepatic insulin sensitivity. Abu-Gazala S#, Horwitz E#, Ben-Haroush Schyr R, Bardugo A, Israeli H, Hija A, Schug J, Shin S, Dor Y, Kaestner KH* and Ben-Zvi D*. Diabetes. Jun; 67(6): 1079-1085 (2018)

4. Angptl4 links adipose tissue triglyceride metabolism with α-cell proliferation. Ben-Zvi D*, Barannadon O, Hadley S, Peterson Q, Blum B, Melton DA*. PNAS. Dec 15, ;112(50):15498:503 (2015)

5. Modeling human nutrition using embryonic stem cells. Ben-Zvi D*, Melton DA*. Cell. Mar 26;161(1):12-7 (2015)

6. Scaling Morphogen Gradients During Tissue Growth by a Cell Division Rule. Averbukh I#, Ben-Zvi D#, Mishra S#, Barkai N. Development. June;141(10): (2014)

7.Self-organized Shuttling: Generating Sharp Dorsoventral Polarity in the Early Drosophila Embryo. Haskel-Ittah M, Ben-Zvi D, Branski-Arieli M, Schejter ED, Shilo BZ*, Barkai N*. Cell. Aug 31;150(5):1016-28 (2012)

8. Expansion-Repression Mechanism for Scaling the Dpp Activation Gradient in the Drosophila Wing Imaginal Disc. Ben-Zvi D, Pyrowolakis G, Barkai N, Shilo BZ. Current Biology. Aug 23 21(16):1391-6 (2011)

9. Scaling of Morphogen Gradients by an Expansion-Repression Integral Feedback Control. Ben-Zvi D, Barkai N. PNAS. Apr 13 107(15):6924-9 (2010)

10. Scaling of the BMP Activation Gradient in Xenopus Embryos. Ben-Zvi D, Shilo BZ, Fainsod A*, Barkai N*. Nature. Jun. 26: 453(1799):1205-11 (2008)