夏芳芳

上海市病毒研究院助理研究员

Email：xiafang09@126.com

博士毕业于上海交通大学，之后分别于上海交通大学医学院仁济医院分子医学研究院谭蔚泓院士课题组、美国Rice Universtiy、以及MD Anderson Cancer Center从事博士后工作。

研究方向：

疫苗佐剂开发、病毒检测

科研项目：

1. 上海市白玉兰人才计划浦江项目，23PJD071，用于胃癌靶向诊疗的自组装纳米药物开发，2023.10-2025.09，主持

2. 中国博士后科学基金第68批面上资助，2020M681333，金团簇-核酸适体药物偶联物纳米组装体用于肿瘤靶向诊治，2020.11-2021.12，结题，主持

3. 科技部, 国家重点研发项目子课题, 2023YFD1802602-2, 基于微流控技术的可降解纳米锰佐剂研制, 2023-12 至 2027-12, 在研, 参与

4. 上海市扬帆计划，20YF1424500, 智能糖基碳量子点用于靶向光驱动治疗类风湿性关节炎，2020.7-2023.6，结题，参与

5. 国家重点研发计划“纳米科技”重点专项，2017YFA0205400，胃癌早期筛查与全病程检测的纳米技术与转化研究，2017.7-2022.6，结题，参与

6. 国家青年基金，81803094，纳米二氧化锰标记的iPS细胞用于胃癌的精准诊疗及其机制研究，2018.1-2018.12，结题，参与

发表论文：

1. A he^#, F Xia^#, Q Yang^*, W Tan^*. Self-assembled amphiphilic NIR-II emissive nano-micelles for imaging-Guided photothermal therapy of colorectal cancer. Science China Chemistry. Accepted.

2. Y Hu, T Guo, F Xia^*, Z Wang^*, W Wang^*, S Ma^*. Removal of Pb (II) from aqueous solution using zirconium phosphate-doped walnut shell biochar modified by a drop-coating method. Journal of Environmental Chemical Engineering. 2023, 11, 5, 110964-110973.

3. F Xia, A He, H Zhao, Y Sun, Q Duan, S Abbas, J Liu^*, Z Xiao^* and W Tan^*. Molecular engineering of aptamer self-assemblies increases in vivo stability and targeted recognition. ACS Nano, 2022, 16, 1, 169–179.

4. F Xia^#, W Hou^#, C Zhang^*, X Zhi, J Cheng, J Fuente, J Song^*, D Cui^*. pH-responsive gold nanoclusters-based nanoprobes for lung cancer targeted near-infrared fluorescence imaging and chemo-photodynamic therapy. Acta biomaterialia, 2018, 68: 308-319.  

5. F Xia, W Hou, Y Liu, W Wang, Y Han, M Yang, X Zhi, C Li, D Qi, T Li, J Fuente, C Zhang, J Song^*, D Cui^*. Cytokine induced killer cells-assisted delivery of chlorin e6 mediated self-assembled gold nanoclusters to tumors for imaging and immuno-photodynamic therapy. Biomaterials, 2018, 170: 1-11.

6. F Xia, J Niu, Y Hong, C Li, W Cao, L Wang, W Hou, Y Liu^*, D Cui^*. Matrix metallopeptidase 2 targeted delivery of gold nanostars decorated with IR-780 iodide for dual-modal imaging and enhanced photothermal/photodynamic therapy. Acta biomaterialia, 2019, 89: 289-299.

7. W Hou^#, F Xia^#, G Alfranca, H Yan, X Zhi, Y Liu, C Peng^*, C Zhang^*, J Fuente, D Cui^*. Nanoparticles for multi-modality cancer diagnosis: simple protocol for self-assembly of gold nanoclusters mediated by gadolinium ions. Biomaterials, 2017, 120: 103-114.

8. Wang C^#, Zhou Z^#, Song W, Cai Z, Ding Z, Chen D^*, Xia, F^*, He, Y^*. Inhibition of IKKβ/NF-κB signaling facilitates tendinopathy healing by rejuvenating inflamm-aging induced tendon-derived stem/progenitor cell senescence. Molecular Therapy-Nucleic Acids, 2022, 27, 562-576.

Yang L, Tang J, Yin H, Yang J, Xu B, Liu Y, Hu Z, Yu B^* Xia F^*, Zou G^*. Self-assembled nanoparticles for tumor-triggered targeting dual-mode NIRF/MR imaging and photodynamic therapy applications. ACS Biomaterials Science & Engineering, 2022, 8(2):880-892.