Name: Haodong LIU, Post Doc
Email: liuhd@sjtu.edu.cn
Office Tel: 021-63846590*776974
Research Interest: Pet microbiome, Marine microbiology, Multiple-omics
Doctor Liu is a postdoctoral fellow of medical microbiology at School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine. After earning his PhD degree, he went on his postdoctoral fellow to study marine microbiology in South University of Science and Technology of China & University of Science and Technology of China. Dr. Liu become more interested in medical microbiology when he finished his first postdoctoral research. So he decided to begin the second postdoctoral research to study medical microbiology since 2021. He was very familiar with bioinformatic analysis, including comparative genomics, metagenomics, transcriptomics of bacteria, archaea and virus. He has been a principal investigator for a Youth Foundation of National Natural Science Foundation of China. His research fields focus on the microbial community structure, antimicrobial resistance genes and other functional genes as well as the interactive relationship and evolution of environmental, human and animal microbiota.
Microbiota of pets and their owners. In recent years, pets ownership is becoming very popular with the development of economy and the improvement of living standard. On one hand, pets can promote the mental health of owners by the companion. On the other hand, the microbes and the antimicrobial resistance genes are easily exchanged through mutual dissemination between pets and owners. Based on bioinformatic analysis, Dr. Liu can do the following researches: (1) to investigate the microbial community and detect the pathogen through metagenomic analysis; (2) to determine the antimicrobial resistance genes and analyze the lateral gene transfer between microbes of human and pets using comparative genomics; (3) to construct the coevolutionary pathways of the microbial community and important functional genes of microbes in pets, owners and environments in one health perspective.
Marine bacteria, archaea and phages. Marine is a huge gene pool of bacteria, archaea and phages. But we still know only a very little part of them. Dr. Liu has studied marine microbiota for several years using methods such as molecular biology, biogeochemistry and bioinformatics. He is the principal investigator for a Youth Foundation of National Natural Science Foundation of China, which is investigating the horizontal transfer of the proteorhodopsin gene in Marine Group II archaea and the organisms’ functional evolution in ecology. In the following research work, he wants to continue doing more studies on marine bacteria, archaea and phage using multiple-omics. In further, he is interested in the research field of how marine bacteria, archaea and phages influence the global climate change as well as the living environment of human.
Publications
[1] Liu H, Zhang C, Tian J. (2016). To investigate the mystery of life in the deepest ocean. Ocean World (11), 64-67.
[2] Liu H, Zhang C, Yang C, Chen S, Cao Z, & Zhang Z, et al. (2017). Marine group II dominates planktonic archaea in water column of the northeastern South China Sea. Frontiers in Microbiology, 8, 1098.
[3] Zhang Y, Liang P, Xie X, Dai X, Liu H, & Zhang C, et al. (2017). Succession of bacterial community structure and potential significance along a sediment core from site u1433 of iodp expedition 349, South China Sea. Marine Geology, 394.
[4] Chen Y, Zheng F, Chen S, Liu H, Phelps TJ, & Zhang C (2018). Branched gdgt production at elevated temperatures in anaerobic soil microcosm incubations. Organic Geochemistry, 117, 12-21.
[5] Graw MF, D'Angelo G, Borchers M, Thurber AR, Johnson JE, Zhang C, Liu H, Colwell, R. K. (2018). Energy gradients structure microbial communities across sediment horizons in deep marine sediments of the South China Sea. Frontiers in Microbiology, 9.
[6] Liu H, Yan R, Zhang C. A mini-review on recent advances in marine group II archaea research. Acta Microbiologia Sinica, 2020, 60(9): 1834-1851.
[7] Chen S, Wang P, Liu H, et al. Population dynamics of methanogens and methanotrophs along the salinity gradient in Pearl River Estuary: implications for methane metabolism. Applied Microbiology and Biotechnology, 2020, 104(3): 1331-1346.
[8] Wang W, Tao J, Liu H, et al. Contrasting bacterial and archaeal distributions reflecting different geochemical processes in a sediment core from the Pearl River Estuary[J]. AMB Express, 2020, 10(1): 16.
[9] Zheng F, Chen Y, Xie W, Chen S, Liu H, et al. Diverse biological sources of core and intact polar isoprenoid GDGTs in terrace soils from southwest of China: Implications for their use as environmental proxies. Chemical Geology, 2019, 522, 108-120.
[10] Wu W, Xu Y, Hou S, Dong L, Liu H, et al. Origin and preservation of archaeal intact polar tetraether lipids in deeply buried sediments from the South China Sea. Deep Sea Research Part I: Oceanographic Research Papers, 2019, 152, 103107.