老年精神疾病诊治中心
上海交通大学医学院附属精神卫生中心老年精神疾病诊治中心成立于1982年，原名老年精神科。该诊治中心设有5个病房，共有329张病床，为病人提供门诊和住院服务。住院部收治的疾病比例包括40%的各种痴呆亚型病人、30%的抑郁症、10%的谵妄、10%的精神分裂症和10%的其他器质性疾病。医师的日常职责包括临床工作、医学生教育、精神科医生继续教育、住院医师和护士的老年精神病学培训，以及专注于老年性精神障碍（如阿尔茨海默病、轻度认知障碍、老年抑郁症等）和迟发性精神分裂症的诊断和治疗研究。诊治中心使用了多种研究技术，如流行病学分析、神经心理学、生物化学、脑成像、脑诱发电位和分子遗传学等对疾病的发病机制、临床特征和干预治疗进行深入研究。
自1998年以来，上海交通大学医学院附属精神卫生中心老年精神疾病诊治中心一直在努力进行诊断和治疗老年期痴呆的临床实践和疾病相关研究。鉴于痴呆是重要的老龄化社会疾病负担和我们诊治中心已有的诊疗优势，上海交通大学阿尔茨海默病及相关疾病诊治中心（ADRDC）作为首批专病诊治中心之一于2009年1月16日正式成立。肖世富教授为ADRDC和老年精神疾病诊治中心主任。ADRDC相关的其他参加单位包括上海交通大学医学院附属仁济医院神经科、上海交通大学附属第六人民医院老年科和上海交通大学附属第一人民医院老年科。ADRDC的目标是整合附属医院的临床资源，规范阿尔茨海默病的诊断和治疗过程，加强研究和学术交流，提高阿尔茨海默病和其他相关痴呆的诊断和治疗能力。
肖世富为上海交通大学医学院附属精神卫生中心老年精神疾病诊治中心主任和上海交通大学阿尔茨海默病及相关疾病诊治中心主任。他还兼任中国老年医学会和中国阿尔茨海默病协会副主任委员、中国心理健康学会心理评估委员会副主任委员、中国精神病学协会理事、老年精神病学委员会副主任委员。肖世富教授还是中国神经病学协会认知与痴呆委员会的成员。肖教授目前是一项大型队列研究的领导者和设计者，该项目的目的是通过大数据分析获得阿尔茨海默病患病风险因素，结合认知评估，建立的临床资料库和生物样本库，以更早发现疾病，帮助老年人建立科学合理的慢病干预方法及自我管理方案，减轻亲属及社会的负担，该项目目前由上海东方脑医学基金会资助。肖教授还曾承担数个国家科技部和上海市科学技术委员项目，对阿尔茨海默病进行综合性研究。肖教授主持国家科技重大专项，是甘露寡糖二酸（GV-971）II期和III期临床试验的设计者和领导者。肖教授还曾接受了美国斯坦利医疗机构的2项资助，并以PI或CO-PI的身份，在过去的十年中进行了超过10项由国家食品药品监督管理局批准的临床试验。
肖教授是100多篇同行评议期刊文章的作者或共同作者，编辑或贡献了36本科学著作。肖教授获得的荣誉包括：世界卫生组织中国神经科学与精神病学最佳论文奖（1991年），中国医学会全国青年医师最佳论文奖（1992年），粟宗华基金会精神卫生研究奖（1996年），上海市政府科技进步奖（1996年，1998年），上海市卫计委银蛇奖（1997年），中华人民共和国国务院津贴奖（2000年），中国精神病学协会最佳论文奖（2002年），中国精神病学协会论文奖（2006年），上海市最佳医务工作者（2008年），高等院校科技进步一等奖（2016年），上海市科技进步一等奖（2017年）。
Geriatric Psychiatry
The Geriatric Mental Disease Diagnosis and Treatment Center, formerly known as geriatric psychiatry department, at the Shanghai Mental Health Center was established in 1982. The department has 5 wards with 329 beds and provides both outpatient and inpatient services for patients. The proportion of disorders seen on the inpatient unit include about 40% with different sub-types of dementia, 30% with depressive disorders, 10% with delirium, 10% with schizophrenia and 10% with other organic disorders. The physician’s daily duties include clinical work, education of medical students, continuing education for general psychiatrists, training in geriatric psychiatry for residents and nurses, and research focused on the diagnosis and treatment geriatric mental disorders such as Alzheimer's disease, Mild Cognitive Impairment, geriatric depression, and late onset Schizophrenia. The department uses a variety of research techniques, such as analysis of epidemiology, neuropsychology, biochemistry, brain imaging, brain evoked potential, and molecular genetics, along with other techniques not discussed.
Since 1998, there has been an ongoing effort to diagnose and treat dementia in the Elderly. Because of this important task, the Alzheimer's Disease and Related Disorders Center (ADRDC) at Shanghai Jiaotong University was formally established in January 16, 2009. Professor Xiao Shifu leads both ADRDC and the Geriatric Mental Disease Diagnosis and Treatment Center at the Shanghai Mental Health Center. Other departments affiliated with the ADRDC include the neurology department at Renji Hospital, the geriatric department of the Sixth People's Hospital, and the geriatric department of the First People's Hospital, all affiliated teaching hospitals of Shanghai Jiaotong University. The aim of the ADRDC and its staff is to integrate the clinical resources of the affiliated medical centers, to standardize the process of diagnosis and treatment of Alzheimer's disease, to enhance research and academic exchange and to improve the ability to diagnose and treat Alzheimer's disease and other related dementia illnesses.
Xiao Shifu is the Professor and Director of the Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine and the Professor and Director of Alzheimer Disease and Related Disorders Center, Shanghai Jiaotong University. He also is the Vice Chair of the Chinese Geriatrician Association and Alzheimer Disease China (ADC) Association, Vice Chair of the Chinese Mental Health Society’s Psychological Evaluation Committee, a board member of the Chinese Psychiatry Association and Vice Director of the Old Age Psychiatry Committee. Finally, Prof. Xiao is a member of the Chinese Neurology Association’s Cognition and Dementia Committee. Prof. Xiao currently is the Principal Investigator in a large study attempting to improve the early recognition and intervention of common psychological disorders in old age. This project is currently funded by the Shanghai Oriental Brain Medical Foundation. Prof. Xiao has also received funds from the Shanghai Science and Technology Committee for two different projects, to conduct clinical research on a new anti-Alzheimer’s drug and a comprehensive study on the diagnosis and possible treatment of MCI in the elderly. Prof. Xiao is also co-PI in an investigation contributing to new technology which will be used in medication trials for treating neurodegenerative disease and mental disorders. The latter study is funded by the China Science and Technology Ministry. Finally, Prof. Xiao received 2 grants from the Stanley Medical Institution of USA, and as PI or Co-PI and conducted more than 10 clinical trials approved by SFDA in the last decade. Prof. Xiao was the leading PI of phase II and phase III clinical trial of oligomannurarate (GV-971).
Prof. Xiao is author or co-author of more than 100 peer-reviewed journal articles and has edited or contributed to 36 scientific books. The honors which Prof. Xiao has received include the WHO-China Best Scientific Article Award for Neuroscience and Psychiatry, third place (1991), the National Best Scientific Article Award for a Young Doctor by the Chinese Medical Association, third place (1992), the Mental Health Research Award given by the Su Zonghua Fundation, second place (1996), the Science and Technology Advance Award given by the Shanghai government, second place (1998), the Silver Snake Award awarded by the Shanghai government (1997), the State Council Allowance Award awarded by the State Council of P. R. China (2000), the Best Scientific Article Award awarded by Chinese Psychiatry Association (2002), the Best Scientific Article Award given by the Chinese Psychiatry Association (2006), the Science and Technology Advance Award given by the Shanghai government, second place (2006), the Best Medical Worker of Shanghai as determined by the Shanghai Health Bureau (2008), the first prize of Science Technology Improvement Award of Science Research Famous Achievement Award in Higher Institution (2016) and the first prize for Shanghai Scientific and Technological Progress (2017).
