上海市耳鼻疾病转化医学重点实验室

上海交通大学医学院耳科学研究所

上海交通大学医学院耳科学研究所成立于2008年10月，2014年经上海市科委批准建设上海市耳鼻疾病转化医学重点实验室，由吴皓教授担任所长和主任。研究所依托上海交通大学医学院、上海交通大学医学院附属第九人民医院，汇聚了一批耳科与听觉医学优秀科学家和中青年人才，现有博士生导师8名、硕士生导师5名，兼聘教授3名。近年来先后获得科技部973重大科学研究计划、国家重点研发计划、国自然重点项目、上海市科委重大项目等多项基金支持，在国际学术期刊上发表SCI论文200多篇。相关研究成果获2018年国家科技进步二等奖，2019年教育部科技进步一等奖等。

研究所聚焦于耳科与听觉医学的基础和转化研究，相继建立了基因测序、听觉电生理、超微结构、质谱、生物成像、生物样本库等技术平台。研究所具备国际一流的实验设施和技术团队，以“感音神经性听觉损伤与修复”为研究核心，针对感音神经性耳聋防治中的关键科学问题，聚焦于听觉信号处理的结构与功能基础，阐明听觉障碍的病理生理机制，发现药物、基因治疗靶点，研发人工听觉植入装置，实现有效听觉重建。

实验室联系人

姓名：高云鸽

电话：021-3845 2258

邮箱：yungegao@126.com

Shanghai Key Laboratory of Translational Medicine on Ear and Nose diseases

Ear Institute, Shanghai Jiaotong University School of Medicine

Ear Institute Shanghai Jiaotong University School of Medicine was founded in October 2008. In 2014, it was approved by Shanghai Committee of Science and Technology to establish Shanghai Key Laboratory of Translational Medicine on Ear and Nose diseases, with Professor Wu Hao as the director. Supported by Shanghai Jiaotong University School of Medicine and Shanghai Ninth People's Hospital, ear institute brings together a group of top scientists and young talents in otology and audiology. Currently, There are 8 doctoral tutors, 5 master tutors and 3 adjunct professors. In recent years, it has got many grants from National Program on Key Basic Research (973 Program), National Key Research and Development Plan, Key Program of National Natural Science Foundation of China, Major Program of Shanghai Committee of Science and Technology, etc, with over 200 SCI papers published in international academic journals. It received National Grade ⅡPrize of Science and Technology Progress in 2018 and Grade Ⅰ Prize of Science and Technology Progress Award of National Ministry of Education in 2019.

The institute focuses on the basic and translational research of otology and audiology medicine, and has successively established 6 technology platforms, include gene sequencing platform, auditory electrophysiological platform, auditory ultrastructural platform, mass spectrometry platform, bioimaging platform and biobank of hearing loss. It owns an international first-class experimental facility and research team. Take the research of “Sensorineural Hearing Loss and Reestablish” as the core, we aim to pursuit key scientific quests on prevention and treatment of sensorineural hearing loss. With focuses on structural and functional basis of auditory signaling process, we want to elucidate the physiopathological mechanism behind hearing impairment, to discover targets of pharmaceutical and gene therapies, to develop artificial hearing implantation device, and to achieve restoration of hearing.

Contact

Name: Yunge Gao

Phone: 021-3845 2258

Email: yungegao@126.com