姓名：郑俊克

研究方向：造血干细胞代谢调控

教育经历：

2002/09-2007/07上海交通大学发育生物学博士（硕博连读）

1995/09-2000/07上海第二医科大学临床医学本科

工作经历：

2012/06-至今上海交通大学/医学院细胞分化与凋亡教育部重点实验室研究员

2010/10-2012/06美国德州大学西南医学中心生理和发育生物学系Instructor

2007/10-2010/09美国德州大学西南医学中心生理和发育生物学系博士后

2002/09-2007/10上海交通大学/医学院附属新华医院博士研究生

2000/07-2002/09上海第二医科大学基础医学院助教

代表性论文5篇：

1.HaoX, Gu H, ChenC, Huang D, ZhaoY, Xie L, ZouY, ShuH, Zhang Y, He X, Lai X, Zhang X, Zhou B, ZhangCC, Chen GQ, Yu Z, Yang Y,Zheng J.Metabolic imaging reveals a unique preference of symmetric cell division and homing of leukemia-initiating cells in an endosteal niche.Cell Metabolism, 2018，In press

2.Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, He L,Chen Y,Chen H, Luo W, Lu Z, Xie J, Churchill H, Xu Y, Zhou Z, Wu G, Yu C, John S,Hirayasu K, Nguyen N, LiuX, HuangF, LLiL,HDengH,TangH, SadekA, ZhangL,HuangT, ZouY, ChenB, ZhuH, AraseH, XiaN, JiangY, CollinsR, YouM, HomsiJ, UnniN,LewisC, ChenGQ,YX, X. LiaoX, AnZ, ZhengJ, ZhangN, and Zhang CC.LILRB4 signaling in leukemia cellsmediatesT cell suppression andtumor infiltration.Nature, 2018,562(7728):605-609

3.Liu X, Zhang F, Zhang Y, Li X, Chen C, Zhou M, Yu Z, Zhao Y, Hao X, Tang B, Zhu L, Liu G, Xie L, Gu H, Shao H, Xia F, Yin C, Tao M, Xie J, Zhang CC, Yang Y, Sun H, Chen GQ,Zheng J.PPM1K regulates hematopoiesis and leukemogenesis through CDC20-mediated ubiquitination of MEIS1 and p21.Cell Rep,23(5):1461-1475, 2018

4.Zhang Y, Xia F, Liu X, Yu Z, Xie L, Liu L, Chen C, Jiang H, Hao X, He X, Zhang F, Gu H, Zhu J, Bai H, Zhang CC, Chen GQ,Zheng J. JAM3 is required for maintaining the self-renewal of leukemia-initiating cells through LRP5/AKT/b-catenin/CCND1 signaling.J Clin Invest.,128(5):1737-1751, 2018

5.Gu H,Chen C,Hao X,Wang C,Zhang X,Li Z,Shao H,Zeng H,Yu Z,Xie L,Xia F,Zhang F,Liu X,Zhang Y,Jiang H,Zhu J,Wan J,Wang C,Weng W,Xie J,Tao M,Zhang CC,Liu J,Chen GQ,Zheng J. Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis.J Clin Invest.,126(12): 4537-4553, 2016