个人简介
徐健，主任医师，博士生导师，国际和平妇幼保健院儿保康复科科主任。入选上海市科委启明星计划、上海市教委高峰高原项目“研究型医师”计划、上海交通大学优秀青年教师等。
社会任职/学术头衔
担任上海市微量元素学会秘书长、中国福利会宋庆龄儿童发展中心兼职教授、中华医学会公共卫生分会青年委员会副主任委员、Neuroscience bulletin杂志青年编委等。
主要研究方向
致力于儿童保健和环境健康交叉领域的重要问题和难点问题。长期进行儿童重金属暴露、儿童微量元素营养、儿童神经心理发育障碍（如智能发育落后、多动症、自闭症、抽动症及其他相关心理行为认知问题）的研究。
主要研究课题
主要是利用出生队列、临床研究、基础研究等方式，系统进行了包括（1）生命早期重金属暴露对儿童神经心理发育的影响及影响机制研究：如生命早期铅、汞、锰暴露。（2）生命早期不良的精神情绪压力对儿童神经心理发育的影响及影响机制研究。
主要研究成果
在Science of the Total Environment、The International Journal of Hygiene and Environmental Health、Environmental Health Perspectives、Ecotoxicology and Environmental Safety、Environmental Research、Environ International、The Journal of Pediatrics、obesity、Developmental Cognitive Neuroscience、Child Adolesc Psychiatry Ment Health。等SCI期刊发表50多篇论文。主译/副主译/参编6本领域内专著。作为负责人主持国家自然基金项目4项。
近5年主要论文：
1. Yu T, Xu D, Fan J, Hua H, Guo X, Zhang Y, Jiang S, Huang L, Jiang Y, Wang Y, Yan C, Xu J* (徐健). Homework, sleep insufficiency and adolescent neurobehavioral problems: Shanghai Adolescent Cohort. J Affect Disord. 2023 Jul 1;332:273-282. doi: 10.1016/j.jad.2023.04.008. Epub 2023 Apr 12. PMID: 37059191.
2. Yu T, Jiang Y, Fan J, Guo X, Hua H, Xu D, Wang Y, Yan C, Xu J* (徐健). Rapid increases in BMI waist to height ratio during adolescence and subsequent neurobehavioral deficits. Obesity (Silver Spring). 2023 Nov;31(11):2822-2833. doi: 10.1002/oby.23881. Epub 2023 Sep 21. PMID: 37735781.
3. Hua H, Huang L, Yang B, Jiang S, Zhang Y, Liu J, Yan C, Xu J* (徐健). The mediating role of gut microbiota in the associations of prenatal maternal combined exposure to lead and stress with neurodevelopmental deficits in young rats. Ecotoxicol Environ Saf. 2023 Apr 15;255:114798. doi: 10.1016/j.ecoenv.2023.114798. Epub 2023 Mar 20. PMID: 36948003.
4. Peng, JY; Gao, ZY; Xu J* (徐健); Lin, YF; Specht, AJ; Chen, SW; Nie, LH ; Huang, LH ; Yan, CH*. Concurrent Assessment on Blood Lead in Young Children and Toy Lead in Shanghai. EXPOSURE AND HEALTH. 2023.DOI10.1007/s12403-023-00582-9
5. Yu T, Xu J* (徐健), Jiang Y, Hua H, Zhou Y, Guo X. School educational models and child mental health among K-12 students: a scoping review. Child Adolesc Psychiatry Ment Health. 2022;16(1):32. doi:10.1186/s13034-022-00469-8.
6. Guo X#, Jiang S#, Xu J Xu J* (徐健), Tian Y, Ouyang F, Yu X, Liu J, Yan C, Zhang J; Shanghai Birth Cohort. Effects of single and combined exposure to lead and stress during pregnancy on offspring neurodevelopment. Developmental Cognitive Neuroscience. 2022; 56:101124. doi:10.1016/j.dcn.2022.101124.
7. Guo X, Wang H, Xu J (徐健)*, Hua H. Impacts of vitamin A deficiency on biological rhythms: Insights from the literature. Front Nutr. 2022 Nov 18;9:886244.
8. Yu T, Zhou L, Xu J* (徐健), Kan H, Chen R, Chen S, Hua H, Liu Z, Yan C. Effects of prenatal exposures to air sulfur dioxide/nitrogen dioxide on toddler neurodevelopment and effect modification by ambient temperature. Ecotoxicol Environ Saf. 2021;230:113118. doi:10.1016/j.ecoenv.2021.113118.
9. Guo X#, Zhou Y#, Xu J* (徐健), Hu Y, Liu Z. The Association of Maternal Emotional Status With Child Over-Use of Electronic Devices During the COVID-19 Pandemic. Front Pediatr. 2021;9:760996. doi:10.3389/fped.2021.760996
10. Guo X, Zhou L, Xu J* (徐健), Liu Z, Liu J, Yan C. Prenatal Maternal Low Selenium, High Thyrotropin, and Low Birth Weights. Biol Trace Elem Res. 2021;199(1):18-25. doi:10.1007/s12011-020-02124-9
11. Huang L#, Jiang S#, Xu J* (徐健), Lei X, Zhang J. Associations between prepregnancy body mass index, gestational weight gain and weight catch‐up in small‐for‐gestational‐age children. Maternal & Child Nutrition. Published online July 22, 2021. doi:10.1111/mcn.13235
12. Guo X#, Hua H#, Xu J* (徐健), Liu Z. Associations of childhood unintentional injuries with maternal emotional status during COVID-19. BMC Pediatrics. 2021;21(1):422. doi:10.1186/s12887-021-02846-2.
13. Li MM, Gao ZY, Dong CY, Wu MQ, Yan J, Cao J, Ma WJ, Wang J, Gong YL, Xu J* (徐健), Cai SZ, Chen JY, Xu SQ, Tong S, Tang D, Zhang J, Yan CH. Contemporary blood lead levels of children aged 0-84 months in China: A national cross-sectional study. Environ Int. 2020;134:105288. doi:10.1016/j.envint.2019.105288
14. Zhang Y#, Zhou L#, Li S, Liu J, Sun S, Ji X, Yan C, Xu J* (徐健). Impacts of lead exposure and chelation therapy on bone metabolism during different developmental stages of rats. Ecotoxicol Environ Saf. 2019;183:109441. doi:10.1016/j.ecoenv.2019.109441.
15. Xu J* (徐健), Hu H*, Wright R, Schnaas L, Bellinger DC, Park SK, Wright RO, Téllez-Rojo MM. Prenatal lead exposure modifies the association of maternal self-esteem with child adaptive ability. Int J Hyg Environ Health. 2019;222(1):68-75. doi:10.1016/j.ijheh.2018.08.005
16. Lin Y#, Huang L#, Xu J* (徐健), Specht AJ, Yan C, Geng H, Shen X, Nie LH*, Hu H. Blood lead, bone lead and child attention-deficit-hyperactivity-disorder-like behavior. Sci Total Environ. 2019;659:161-167. doi:10.1016/j.scitotenv.2018.12.219
17. Jiang S#, Yang B#, Xu J* (徐健), Liu Z, Yan C, Zhang J, Li S, Shen X. Associations of Internal-Migration Status with Maternal Exposure to Stress, Lead, and Selenium Deficiency Among Pregnant Women in Shanghai, China. Biol Trace Elem Res. 2019;190(2):309-317. doi:10.1007/s12011-018-1570-0
18. Huo X, Chu S, Hua L, Bao Y, Du L, Xu J Xu J* (徐健), Zhang J*. The effect of breastfeeding on the risk of asthma in high-risk children: a case-control study in Shanghai, China. BMC Pregnancy Childbirth. 2018;18(1):341. doi:10.1186/s12884-018-1936-5
19. Specht AJ, Lin Y, Xu J (徐健), Weisskopf M, Nie LH. Bone lead levels in an environmentally exposed elderly population in shanghai, China. Sci Total Environ. 2018;626:96-98. doi:10.1016/j.scitotenv.2018.01.091
20. Ying XL, Gao ZY, Yan J, Zhang M, Wang J, Xu J Xu J (徐健), Markowitz M, Yan CH. Sources, symptoms and characteristics of childhood lead poisoning: experience from a lead specialty clinic in China. Clin Toxicol (Phila). 2018;56(6):397-403. doi:10.1080/15563650.2017.1391392
21. Lin Y, Xu J Xu J* (徐健), Huang J, Jia Y, Zhang J, Yan C, Zhang J. Effects of prenatal and postnatal maternal emotional stress on toddlers’ cognitive and temperamental development. J Affect Disord. 2017;207:9-17. doi:10.1016/j.jad.2016.09.010
22. Li S, Xu J* (徐健), Liu Z, Yan CH. The non-linear association between low-level lead exposure and maternal stress among pregnant women. Neurotoxicology. 2017;59:191-196. doi:10.1016/j.neuro.2016.07.005
23. Zhou L, Xu J Xu J* (徐健), Zhang J, Yan C, Lin Y, Jia Y, Hu W. Prenatal maternal stress in relation to the effects of prenatal lead exposure on toddler cognitive development. Neurotoxicology. 2017;59:71-78. doi:10.1016/j.neuro.2017.01.008
24. Specht AJ, Mostafaei F, Lin Y, Xu J* (徐健), Nie LH*. Measurements of Strontium Levels in Human Bone In Vivo Using Portable X-ray Fluorescence (XRF). Appl Spectrosc. 2017;71(8):1962-1968. doi:10.1177/0003702817694383
25. Lin Y#, Zhou L#, Xu J Xu J* (徐健), Luo Z, Kan H, Zhang J, Yan C, Zhang J. The impacts of air pollution on maternal stress during pregnancy. Scientific Reports. 2017;7(1):40956. doi:10.1038/srep40956
26. Lin Y, Hu W, Xu J Xu J* (徐健), Luo Z, Ye X, Yan C, Liu Z, Tong S. Association between temperature and maternal stress during pregnancy. Environmental Research. 2017;158:421-430. doi:10.1016/j.envres.2017.06.0
