2019 SHIPM Symposium

Shanghai Institute of Precision Medicine (SHIPM)

Grand Ballroom A, Holiday Inn Shanghai Jin Xiu (399 Jinzun Road, Pudong New District, Shanghai)

Day One Oct. 24, 2019 Thursday

Opening Remark and Keynote Speach Hosted by Prof. Ming Lei (SHIPM)

Opening Remark

9:00-9:10

Opening Remark by Hao Wu (Director, SHIPM; President, Ninth People's Hospital, SJTUSM)

Keynote Speech

1

9:10-9:50

Zihe Rao (Tsinghua University, China)

TBA

Session One Chairman: Prof. Alex Chang (SHIPM)

Precision Medicine - from bench to bedside in the era of big data

2

9:50-10:20

Aly Karsan (The University of British Columbia, Canada)

Tailoring therapy for leukemia patients

10:20-10:40

coffee / tea break & group photo

3

10:40-11:10

Rong Tian (University of Washington, USA)

Mitochondrial Medicine: Challenges and Opportunities

4

11:10-11:40

Vincent Geli (Cancer Research Centre of Marseille, France)

The p21-mTert knock-In mouse: a model of senescence bypass in lung disease and much more

5

11:40-12:10

Alex Chang (SHIPM,Ninth People's Hospital, SJTUSM, China)

Accelerated aging in genetic cardiomyopathy

12:10-13:30

Working Lunch

Session Two Chairman: Prof. Yunfeng Hua (SHIPM)

from Cochlea to Auditory Brainstem

6

13:30-14:00

M. Charles Liberman (Harvard Medical School, USA)

Cochlear nerve degeneration in human presbycusis: evidence for hidden hearing loss in the aging ear.

7

14:00-14:30

George Spirou (University of South Florida, USA)

Building a high-resolution synaptic map of a CNS neural circuit to explore temporal coding of sound

8

14:30-15:00

Vladan Rankovic (University Medical Center Göttingen, Germany)

Towards optical cochlear implant - Optogenetic stimulation of the auditory pathway

15:00-15:15

coffee / tea break

9

15:15-15:45

Ana Belén Elgoyhen (National Council for Scientific and Technology Research, Argentina)

The Efferent Olivocochlear System and Development of Central Auditory Circuits

10

15:45-16:15

Yunfeng Hua (SHIPM,Ninth People's Hospital, SJTUSM, China)

Electron Microscopic Reconstruction of Mammalian Cochlear Circuit

Day Two Oct. 25, 2019 Friday

Session Three Chairman: Prof. Ming Lei (SHIPM)

RNA Biology

11

9:00-9:30

Christopher D. Lima (Memorial Sloan Kettering cancer Center, USA)

Helicase-dependent RNA decay

12

9:30-10:00

Jing Huang (SHIPM,Ninth People's Hospital, SJTUSM, China)

Structural basis for histone modifications on nucleosomes

13

10:00-10:30

Venkat Gopalan (The Ohio State University, USA)

Dissecting protein-aided RNA catalysis in archaeal RNase P,

an ancient tRNA processing enzyme

10:30-10:45

coffee / tea break

14

10:45-11:15

Xiang-Dong Fu (University of California, San Diego, USA)

Making New Neurons in the Brain

15

11:15-11:45

Yunyu Shi (The University of Science and Technology of China)

Structural insights into the recognition of γ-globin gene promoter by BCL11A

16

11:45-12:15

Guoqing Li (Leica Microsystems)

Leica cutting-edge technology in nanoscopy and multiphoton imaging

12:15-13:30

Working Lunch

17

13:30-14:00

Noam Shomron (Tel Aviv University, Israel)

Machine-learning RNA-driven decisions

18

14:00-14:30

Dinshaw Patel (Memorial Sloan Kettering cancer Center, USA)

Structural Biology of CRISPR-Cas Surveillance Complexes

Session Four Chairman: Prof. Yu Cao (SHIPM)

Cell Therapy and Targeted Medicine

19

14:30-15:00

Vanita Sood (EMD Serono, Inc., USA)

Inventing better drugs: Use of AI & Machine Learning in Small Molecule & Biologics Discovery

15:00-15:20

coffee / tea break

20

15:20-15:50

Weiping Zou (University of Michigan School of Medicine, USA)

Metabolic impact on cancer immunity and therapy

21

15:50-16:20

Xiayang Qiu (CEO/CSO, Regor Therapeutics Inc)

Mission Precision - Structural Insights Accelerate Target Validation and Medicine Design

16:20-16:30

Closing Remark by Ming Lei (Exective Director, SHIPM)