PhD Supervisors atInstitute of Health Sciences

Name: GuoFang

Title:PrincipalInvestigator

Department:Biochemistry and molecularbiology

Research Interest:1.The activation ofboth pro-cathepsin L and pro-MMP2 through the combination oflegumain with integrin,and their over-expression;increased tumorinvasion and metastasis; a subset of cell surface anchored orassociated proteases that are drastically over-expressed in highpercentage of human cancers;2. The mechanism and effect oftumor-associated macrophages (TAMs) in the promotion ofmalignant

tumor metastases.

Institute: Institute of HealthSciences,Shanghai Jiao Tong University School ofMedicine

Tel:86-21-63852719

Email: guofang@sibs.ac.cn

Name: JingQing

Title:PrincipalInvestigator

Department:Biochemistry and molecularbiology

Research Interest:Regulation ofmicroRNA and diseases:1. Mechanism of AU-rich Elements directedmRNA degradation on post-tranional gene regulation; 2.Identification of tissue- and cell-specific MicroRNAs incardiovascular systems and their physiological, pathologicalsignificance;

3. Regulation on differentiation of embryonic stem cells tocardiomyocytes, endothelial cells;4. Lipid metabolism and molecularmechanism of atherosclerosis

Institute: Institute of HealthSciences,Shanghai Jiao Tong University School ofMedicine

Tel:86-21-63852710; 86-21-63842973

Email: qjing@sibs.ac.cn

Name: KongXiangyin

Title:PrincipalInvestigator

Department:Genetics

Research Interest:Both genetic factorsand non-genetic environmental factors involved in the developmentof human common diseases;epigenetic regulation in genetic diseasesand tumors.

Institute: Institute of HealthSciences,Shanghai Jiao Tong University School ofMedicine

Tel:86-21-63852639

Email: xykong@sibs.ac.cn

Name: LiuTingxi

Title:PrincipalInvestigator

Department:Genetics

Research Interest:1. Signaltransduction networks and epigenetic regulatory pathways involvedin the self-renewal, differentiation and genome instability ofnormal hematopoietic stem cells and leukemia stem cells;2.Molecular mechanisms underlying chemotactic movement ofinflammatory blood cells and metastasis of cancer stem cells;3.Whole animal-based high throughput screen with zebrafish forpotential therapeutic drugs

Institute: Institute of HealthSciences,Shanghai Jiao Tong University School ofMedicine

Tel:86-21-63855944,86-21-63843462

Email: txliu@sibs.ac.cn tingxi.liu@gmail.com

Name: MaWeijun

Title:PrincipalInvestigator

Department:Biochemistry and molecularbiology

Research Interest:1. Identificationand characterization of cis-acting elements in untranslated region(UTR) of early response genes involved in carcinogenesis and immuneresponse;2. Post-tranional regulation of immediate earlygenes response to drug treatment;3. Analysis ofpost-tranional mechanism activated by signal transductionpathway that regulates gene expression;4. Development of novelstrategy for ligand screening on expressed drug targetprotein.

Institute: Institute of HealthSciences,Shanghai Jiao Tong University School ofMedicine

Tel:86-21-63852596

Email: wjma@sibs.ac.cn

Name: QianYoucun

Title:PrincipalInvestigator

Department:Biochemistry and molecularbiology

Research Interest:Signal transductionin immunity

Institute: Institute of HealthSciences,Shanghai Jiao Tong University School ofMedicine

Tel:86-21-63852804

Email: ycqian@sibs.ac.cn

Name: ShiYufang

Title:PrincipalInvestigator

Department:Cellbiology

Research Interest:1. Molecularmechanisms of activation-induced cell death in T cellsubpopulations; 2. Understanding how immunosuppression is mediatedmesenchymal stem cells;3. Tumor stroma and tumorimmunology

Institute: Institute of HealthSciences,Shanghai Jiao Tong University School ofMedicine

Tel:86-21-63848329

Email: shiyufang2@gmail.com

Name: YangHuangtian

Title:PrincipalInvestigator

Department:CellBiology

Research Interest:1. Identifying thefactors, genes and signal pathways which regulate stem celldifferentiation, especially the differentiation of embryonic stemcells into cardiomyocytes;2. Characterizing embryonic stemcell-derived cardiomyocytes and evaluating their therapeuticimplication;3. Elucidating the regulatory mechanisms of Ca2+signaling and the signal transduction pathways mediated by Gprotein coupled receptors in cardiogenesis and in myocardialcontraction;4. Determining the cellular and molecular basis forhypoxic adaptation-induced cardioprotection against ischemicinjury.

Institute: Institute of HealthSciences, Shanghai Jiao Tong University School ofMedicine

Tel:86-21-63852793

Email: htyang@sibs.ac.cn

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